Lesionectomy for Temporal Lobe Lesion Can Results in Reduced Need of Antiepileptic Drugs.

Hossain Khan, Akhlaque; Chaurasia, Bipin; Rahman, Md.Tauhidur; Dorji, Tandin Wangyel; Bari, Sazzadul; Jha, Alok; Md. Abu Obaida, Abu Saleh; Chavda, Vishal; Montemurro, Nicola; Yeamoon, Atanna; Ahmed, Mamun; Anika, Farheen Khan; Rahman, Asifur

doi:10.21608/pajn.2023.238574.1105

Lesionectomy for Temporal Lobe Lesion Can Results in Reduced Need of Antiepileptic Drugs.

Document Type : Case Reports

Authors

¹ Department of Neurosurgery,BSMMU,Shahbag,Dhaka,Bangladesh

² Department of Neurosurgery,Neurosurgery Clinic ,Birgunj,Nepal

³ Department of Neurosurgery,BSSMU,Shahbag,Dhaka,Bangladesh

⁴ department of neurosurgery,BSMMU,DHAKA,Bangladesh

⁵ Deaprtment of neurosurgery,Bsmmu,Bangladesh

⁶ department of neurosurgery,BSMMU,shahbag,dhaka,bangladesh

⁷ Department of pathology,stanford school of medicine,stanford,USA

⁸ Deapartment of neurosurgery,university of pisa pisa,italy

⁹ BSMMU,Bangladesh

¹⁰ Bsmmu,Bangladesh

10.21608/pajn.2023.238574.1105

Abstract

Background: Seizure outcomes after laminectomy have been proven to be equivalent to excision, which ablates the epileptogenic cortex with the lesion. Different forms of resection surgery, as well as temporal lobectomy, are being investigated as therapeutic options for people with focal epilepsy who have not responded to medication. The median seizure-freedom rate following temporal lobectomy for mesial temporal sclerosis is 70%, with extra-temporal resections and patients with non-lesional epilepsy having a somewhat lower rate. Although seizure control is the primary goal of epilepsy surgery, lowering or quitting antiepileptic medications (AEDs) following epilepsy surgery is also an essential goal for patients and epileptologists. CASE REPORT: We described a thirteen-year-old female who had suffered from headaches and multiple bouts of complex partial seizures for three years before undergoing surgery for a well-circumscribed lesion occupying the medial portion of the left temporal lobe next to the pole with modest compression to the ipsilateral curs of the midbrain. CONCLUSION: Many investigations evaluating seizure outcomes after epilepsy surgery have been undertaken, as well as the impact on health-related quality of life. Because there is minimal evidence from clinical studies of postoperative antiepileptic drug reduction, prospective trials of AED withdrawal following epilepsy surgery should provide more specific information.

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