Pregabalin and mecobalamin combination in the management of refractory neuropathic pain: a potential alternative to early surgery in disco-radicular conflicts.

Document Type : Original Articles

Authors

Neurosurgery Department, Fann’s national teaching hospital, Dakar, Senegal, BP: 5035.

Abstract

Context and Objective: Neuropathic pain is pain resulting from injury to the nervous system. They are said to be peripheral when they are consecutive to a lesion of the peripheral nervous system and can concern a plexus, a root or a truncular attack. The aim of this study is to establish the interest of a combination of Pregabalin and Mechobalamin in the medical management of refractory neuropathic pain in the pre-operative period, and to highlight its advantages.
Patients and methods: This is a cross-sectional analytical study with a duration of 12 months from 30 September 2021 to 30 September 2022. Patients were divided into 2 groups: Pregabalin for group A and Pregabalin + Mecobalamin for group B. Patients who did not receive Pregabalin or Pregabalin + Mecobalamin were not included. Anonymity and confidentiality were preserved. Data were entered into Epi-Info 7.1.4.0 and analysed in STATA/SE 11.2.
Results: In 81.82% of the patients in group A, an indication for surgery was given after three (3) months of evolution against 18.18% of group B in whom surgery was performed after three (3) months of evolution.
Conclusion: This study shows that the fixed combination of pregabalin and mecobalamin gives the neurosurgeon time to prepare the operation. Its "minimal effective dose" power preserves the patient from intoxication and dependence.

Keywords

Files

Share

How to cite

Statistics