Oral anticoagulants can improve the functional outcome in survivors of spontaneous intracerebral hemorrhage.

Document Type : Original Articles

Authors

1 Lecturer at Department of Neurosurgery, Faculty of Medicine, Kasr Al-Ainy Medical College, Cairo, Egypt

2 Department of Neurosurgery, Beni-Suef University, Beni-Suef, Egypt

3 Department of Neurosurgery, Kasr Al Ainy School of Medicine, Cairo University

Abstract

Abstract
Background: Intracerebral hemorrhage (ICH) accounts for 10-30% of strokes worldwide. Anticoagulation has been believed to induce ICH for a long time, however, oral anticoagulants can have beneficial impact, especially on the patient's outcome, this study demonstrates how the history of oral anticoagulant administration can affect the outcome of patients surviving spontaneous intracerebral hemorrhage.
Methods: 93 patients were included in the study.
underwent neurological examination, the size of the hematoma was calculated in Cm3 and the patients’ outcome was estimated using Extended Glasgow Outcome Score (EGOS) one day after surgery, and 4 months later. The statistical analysis was conducted using the Wilcoxon signed ranks test for numeric data, and the Chi Squared test for categorical data, a Cox regression model was used to calculate the degree of correlation.
Results: Among the 92 cases included, 37 were females and 56 were males, age ranged from 18-90 years (mean= 58,26  9.62), 51 patients received anti-coagulation, while 42 did not receive anti-coagulation prior to the onset of the condition, the average size of the hematomas was 42.94 ml( 8.63), larger sizes recorded with the use of anticoagulation (mean = 43.75 7.99) than without anti-coagulation( mean= 41.98  9.36) (p.value

Keywords

Pan Arab Journal of Neurosurgery
Volume 16, Issue 2
December 2021
Pages 64-70

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